Bioidentical Estradiol
Pharmaceutical-grade micronized estradiol — supports brain, bones, mood, vaginal tissue, and long-term vitality.
HSA/FSA Eligible
Try Our Local Estradiol Cream For Your Vaginal Dryness
Starting at$29/month*
Currently in stock
Targeted low-dose estrogen for vaginal comfort and urinary health.
*When you pay for 3 months supply at once
HRT effectively targets over 100 documented menopause symptoms by restoring the hormones your body has stopped producing.
The most common ones women come to Elsie for are hot flashes, night sweats, trouble sleeping, mood swings, anxiety, brain fog, fatigue, low libido, vaginal dryness, joint pain, and weight gain. But many women are surprised to find that symptoms they thought were unrelated also improve.
Thinning hair, crawling skin, heart palpitations, loss of motivation, irritability. These are all connected to your hormones. When your levels are restored, your whole body starts working the way it should again.
Everything you need to get started and stay on track. A full medical consultation with a board-certified doctor. A personalized treatment plan built around your symptoms.
Your medication shipped right to your door. And ongoing access to your provider whenever you have questions or need your dosage adjusted. No hidden fees, no separate consultation charges. If your doctor recommends adding progesterone to your treatment, that's included in your plan too.
Most women start feeling better within 2 to 4 weeks. Hot flashes and night sweats are usually the first to improve, followed by better sleep. Some women notice a difference within days. It differs from person to person.
Mood, energy, mental clarity, and libido tend to keep getting better over the first 2 to 3 months as your body adjusts. Your doctor checks in on your progress and can adjust your dosage to make sure you're getting the best results possible. HRT is not an overnight fix, but most women say they wish they had started sooner.
A low-dose estrogen cream applied directly to the vaginal area. It restores tissue health and moisture locally without significantly raising overall hormone levels.
Ideal for women who experience vaginal dryness, painful intercourse, or urinary symptoms, either alone or alongside systemic HRT.
Apply a small amount to the vaginal area as directed by your physician. Typically used daily for the first few weeks, then reduced to a maintenance dose.
Your doctor will provide a full application guide and dosing schedule based on your specific symptoms.
Trivea® fights the symptoms that stole your spark.
Trivea® supports:
- Clearer thinking and stable moods
- Deeper, more restorative sleep
- Healthier libido and sexual comfort
- Steadier energy and metabolism
- Bone, brain, and cardiovascular protection
- Vaginal health — without a separate cream
This isn't about chasing one symptom at a time.
It's about restoring steady hormone levels so your body can do its actual job.
Stop managing your hormones like a to-do list
Trivea® replaces the patchwork with one steady formula designed for systemic absorption and balanced dosing.
TriveaHormonal cream
One formula.One routine.One price.
Most hormone therapy ends up looking like this:
The other methods
Estrogen patch, progesterone pill, vaginal cream, and sometimes a separate testosterone Rx — each on its own schedule, each from a different prescriber.
TriveaHormonal
Eliminate symptoms in just a few weeks
In an 8-week internal outcome review of women on Trivea®:
94%
reduction in vaginal dryness
83%
improved sleep quality
79%
improved mood
86%
sharper focus and vitality
81%
higher daily energy
These changes track restored hormone levels — not temporary symptom masking.
Our Science
How Trivea® supports your hormones
Estradiol
Supports brain, bones, metabolism, mood, vaginal tissue, and long-term vitality.
Progesterone
Protects the uterine lining, promotes restful sleep, balances estradiol, and supports a calm nervous system.
Estriol
The gentlest of the three estrogens — supports vaginal and skin tissue health, and softens hot flashes without overloading the system.
Bioidentical Progesterone
Protects the uterine lining, supports calmer sleep, and balances estradiol so dosing stays even.
Bioidentical Estriol
The gentlest of the three estrogens — supports vaginal and skin tissue health and softens hot flashes without overloading the system.
Supports natural testosterone
Progesterone acts as a precursor to testosterone. Adequate progesterone leads to adequate testosterone which supports libido, sleep and energy.
Real people, real results
Hear from 5,200+ women
“I can honestly say that after 3 days, I said to my husband — I don’t know how to explain it, but I feel myself again.”
“I already feel a lot of my pain decreasing, I’m sleeping better, and I’m able to mentally focus.”
“My creativity has come back, my brain fog has lifted, I feel more level energy day in and day out.”
“I absolutely adore Trivea. It’s been 6 months now. If you’re thinking about it, stop thinking and just do it.”
“I’ve lost weight, my energy is back, and the depression that hung around for years is finally lifting.”
“One pump every morning. That’s it. I expected something more complicated and I’m grateful it isn’t.”
“By the second week my husband told me I seemed like myself again. It just keeps getting better from there.”
“Six weeks on Trivea and it’s like waking up from a long, foggy dream. I didn’t realize how dimmed I’d become.”
“Sleep first, then mood, then libido. The order surprised me — but every piece came back.”
“My periods went from chaos to predictable in two cycles. Even my dermatologist asked what I changed.”
“The hot flashes are gone. So is the 3am staring-at-the-ceiling. I can’t believe a single cream did all this.”
Our Sources
Designed for long-term confidence
Trivea® is a prescription bioidentical hormone therapy compounded to U.S. pharmacy standards.
What's inside — and how it's made — matters.
Bioidentical Estradiol & Micronized Progesterone
Identical molecules to the hormones your body already makes — easier to absorb, easier to dose, and fewer side effects than synthetic alternatives.
Pharmaceutical-grade active ingredients
Sourced from FDA-registered manufacturers and tested for identity and purity before they ever reach our compounding line.
503A licensed compounding pharmacy
Compounded one prescription at a time in a U.S. pharmacy that holds both NABP and PCAB accreditation — the gold standard for sterile and non-sterile compounding.
Third-party potency testing
Independent labs verify that the dose on the label is the dose in the bottle — every batch, every time, with a Certificate of Analysis on file.
Cold-chain shipping
Insulated packaging keeps your formula stable from the compounding floor to your front door — even in summer heat.
Simple, transparent pricing
Starts at $79 per month.
One price. Stays the same, always.
90-day money-back guarantee*. If you don't feel better in 90 days, it's free.
- Prescription treatment
- Free & fast shipping
- Unlimited clinical follow-up
- HSA / FSA eligible
- No insurance needed, cancel anytime
- Dose adjustments included
Our treatments
Doctor-prescribed bioidentical hormone treatments — personalized to your symptoms.
Trivea® 3-in-1 Cream
$79/moStarting
A personalized hormone cream made for your body. Your doctor picks the exact estrogen and progesterone combo based on your symptoms.
Estradiol Biweekly Patch
$109/moStarting
A small, discreet patch that delivers steady estradiol through the skin all week. Apply and forget — no daily routine needed.
Estradiol Gel
$79/moStarting
A clear, odorless estrogen gel applied daily. Quick pump, quick absorb, gets to work on hot flashes, night sweats, and more.
Progesterone Capsules
$0/moStarting
Included with your prescription when needed. Helps balance estrogen and supports better sleep, mood, and uterine health.
Vaginal Estradiol Cream
$24/moStarting
A low-dose cream applied locally for vaginal dryness, irritation, and discomfort. Works directly where it's needed.
The timeline
What most women notice
Week 2
Improvement in vaginal health, mood and sleep
Week 4
More consistent energy and improved cycle stability
Week 6
Clearer thinking and reduced anxiety.
Week 8
Feeling more like yourself again.
“Why am I so anxious?”
“My mood swings are intense.”
“I’m exhausted no matter how much I sleep.”
“My brain fog just won’t lift.”
“My periods are heavier and unpredictable!”
The truth about testosterone
Do you need added testosterone?
Many women are told testosterone is the missing piece. In a lot of cases, low testosterone shows up as a downstream effect of low progesterone and broader hormonal imbalance — not the root cause.
Trivea® doesn't include added testosterone. Instead, it restores progesterone — which serves as a precursor in your body's own testosterone pathway.
When hormone balance is restored, many women notice improvements in:
- Libido
- Motivation
- Energy
- Muscle tone
Without the risks often associated with testosterone creams, pellets, or injections.
For women who genuinely need additional testosterone, our clinicians can evaluate that separately. Balance first. Add only if necessary.
How it works
Getting started is simple
TriveaHormonal
What brings you to Trivea®?
I have polycystic ovarian syndrome (PCOS)
Don't know — I just don't feel great
I'm experiencing postpartum symptoms
I have endometriosis or suspect that I do
STEP 1
Complete our 2-minute health quiz
Help us understand your symptoms to see if Trivea® is right for you.
TriveaHormonal
Shipped right
to your doorstep.
to your doorstep.
PharmacyPhiladelphia, PAYou2-3 days
Free, discreet packaging
STEP 2
Receive your prescription treatment
Once approved, your formula ships straight to your door. No appointment needed.
TriveaHormonal
Care that's transparent, trustworthy, and centered around you.
Hi! Quick check-in — how's the new dose treating you?
Sleep is way better. Brain fog still some days.
STEP 3
Start treatment and get ongoing support
Our clinical care team is here for you whenever you want to check in.
You're not managing this alone.
Every prescription is reviewed and monitored by a licensed clinician.
Hormones change. Your care adapts.
Unlimited secured messaging
Hi! I need help! I may need a higher dose for my Trivea®!
Sure! Let's get you connected with a clinician to discuss your dose.
Lab review and dose adjustments if needed
Your action planMarch 20 2026
Ongoing monitoring — not one-time prescribing.
TriveaHormonal
Smarter hormone therapy. Finally simplified.
One cream. Two bioidentical hormones. Steady systemic support — without the patchwork.
See if Trivea® is a better fit for you.
Questions?
Treatments & safety
Trivea® uses bioidentical estradiol and micronized progesterone — molecules identical to what your body already makes. It is prescribed and monitored by a U.S.-licensed clinician based on your intake and history.
Modern guidance from menopause specialists supports long-term bioidentical HRT for many women when monitored. Your clinician will check in over time and adjust as your needs change.
Yes. Every batch leaves our pharmacy with a Certificate of Analysis from an independent lab confirming identity, potency, and purity of the active ingredients.
Trivea® is compounded at a 503A licensed U.S. pharmacy that holds NABP and PCAB accreditation — the same standards used to vet hospital and oncology compounders.
Bioidentical. The estradiol and progesterone in Trivea® are molecularly identical to the hormones your ovaries used to produce — derived from plant sources, not synthesized analogs like medroxyprogesterone.
Most HRT regimens require a patch plus an oral progesterone plus sometimes a separate vaginal cream. Trivea® combines the bioidentical hormones in one daily transdermal cream — fewer scripts, simpler routine, steadier levels.
Supplements support hormone production indirectly. Trivea® delivers the actual hormones your body is missing. For symptoms tied to true hormone decline, replacement does what supplements cannot.
Symptoms in perimenopause and menopause often appear before lab values change, and bloodwork at a single point in time can miss the picture. We start treatment from your symptom history and order labs only when they will change the plan.
"Estrogen dominance" usually means estrogen is high relative to progesterone. Trivea® raises progesterone alongside estradiol, so the ratio moves toward balance rather than further imbalance.
Mild breast tenderness, light spotting, or temporary mood shifts can show up in the first cycle as your body adjusts. Most resolve on their own; persistent issues are addressed with a dose adjustment by your clinician.
Trivea® is not a fertility treatment and is not designed to be used while trying to conceive or during pregnancy. If you are planning a pregnancy, talk to your clinician before starting.